Professor Mac, at age 37, find himself jettisoned into an identity crisis. Frankie, a NYC professional dancer, grapples with the spotlight versus settling down and having children. Enrique, a DJ and mechanic, struggles with coming out as a gay man with a hostile father. Immersed in their unique personal dramas, this trio crosses paths in the cobblestone streets and zócalo, or main plaza, of Oaxaca, Mexico. Together they weave a colorful, complex tapestry of adventure, deceit, discovery, love and pain. Frankie volunteers at an orphanage run by Enrique’s uncle. She hopes spending time with children will help her make a decision about family versus performing, but her endeavor is interrupted by an earth-shattering event. Simultaneously, her relationship with a feisty, little girl tugs at her heart as she’s forced to reconcile the personal and the professional. Enrique’s father throws him out of his house, and Enrique flees on his motorcycle to Juchitan. There, he meets Marcos and his muxe friends who crack his world wide open. Back in Oaxaca, Enrique’s life continues to be woven into Mac and Frankie’s in unexpected ways. Mac is on a mission to the pueblo of Lachatao with Frankie as his interpreter, and what he learns there affirms mysterious experiences he’s been having and sends him on a quest to Mexico City. As Frankie and Mac get closer, Mac’s wife, back in the States, struggles with his newly developing identity and relationships. When it’s time for Mac and Frankie to make their respective trips home, like Enrique, they have changed in fundamental ways. But back in the States, their Oaxacan odyssey continues to reverberate and change the course of their lives.