"In your questionnaire, you noted that “every seventy-two seconds, someone in America develops Alzheimer’s disease. And it has been said that almost everyone living long enough will eventually show evidence of Alzheimer’s disease. Thus far, its cause has remained elusive.” That was your motivation for writing this historical nonfiction book. You have developed a comprehensive, fascinating, well-written guidebook on the subject of this all-too-prevalent disease. Your book, with its heavy focus on etiology, will no doubt serve as a go-to guide for many practitioners and researchers. You have documented your argument extremely well, and you have created an admirable blend of science, history, and the real-world reasons why some things happen the way they do in any field of study (e.g., politics). Your analysis of the relationships among the various researchers is extremely interesting. Also, you have written the book in a way that is easy for anyone to understand—not just physicians or researchers."