0f Sin and Soul follows the travails of a young American woman, Chloe Ettagio. Who leaves her home and family behind and escapes her loveless marriage by emigrating to the west coast of Ireland. She embarks on a torrid but disastrous sexual affair once settled there. This affair reshapes the rest of her life. We learn how a singular life event can change our destiny so dramatically. And of the family secrets and the community's efforts to protect those secrets.