The 1991 edition of this book introduced the concept that it is the repetitive-formation of Transient Linear Elements of Hydration on lipid and poly-ionic surfaces that, not only assist in the assembly of proteins and nucleic acids, but in interactions of all molecules in living cells. This edition provides structural evidence that the molecules of life function so smoothly and spontaneously together because they are all spatial homologues of the order/disorder properties of the ionic aqueous environment in which they formed and evolved.